BAG4 and APOBEC1

Number of citations of the paper that reports this interaction (PubMedID 14559896)
9

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		BAG4	APOBEC1
Description		BAG cochaperone 4	apolipoprotein B mRNA editing enzyme catalytic subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding	RNA Binding Cytidine Deaminase Activity Cytosine Deaminase Activity Protein Binding Enzyme Activator Activity Zinc Ion Binding Protein Domain Specific Binding MRNA 3'-UTR AU-rich Region Binding Ribonucleoprotein Complex Binding
	Biological Process	Protein Folding Positive Regulation Of Fibroblast Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Adhesion Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Ruffle Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity	RNA Processing MRNA Processing Lipid Metabolic Process Triglyceride Metabolic Process Response To Osmotic Stress Cytidine Deamination Response To Zinc Ion Response To Gamma Radiation Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Regulation Of Cell Proliferation Lipoprotein Biosynthetic Process Lipoprotein Transport Positive Regulation Of Catalytic Activity Response To Ethanol MRNA Stabilization Response To Calcium Ion Defense Response To Virus DNA Cytosine Deamination DNA Demethylation Negative Regulation Of Triglyceride Metabolic Process Negative Regulation Of Methylation-dependent Chromatin Silencing Positive Regulation Of MRNA Modification
Pathways		Regulation of HSF1-mediated heat shock response Signaling by FGFR1 in disease TNF signaling Signaling by plasma membrane FGFR1 fusions	mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 29483656)	Body mass index ( 28552196) Creatine kinase levels ( 29403010) HDL cholesterol levels ( 28334899)
Interacting Genes		38 interacting genes: APOBEC1 ATAD2 BAP1 BCAS3 BCL2 BEX1 CASZ1 CCL5 DIRAS3 EPSTI1 ERRFI1 GLCE GRAP2 HSPA1A HSPA8 IL13RA2 IL24 ITIH5 KLK5 KLK7 KLK9 LRATD2 LYPD3 MRC2 MTA3 NAT2 PDLIM2 PLAT PRDM14 RASL10B RHOBTB2 RNF20 RPL22 SCGB3A1 TBC1D7 THRSP TNFRSF1A TNFRSF25	8 interacting genes: A1CF APOBEC2 BAG4 CELF2 DNAJB11 DND1 KPNA2 SYNCRIP
Entrez ID		9530	339
HPRD ID		04861	02531
Ensembl ID		ENSG00000156735	ENSG00000111701
Uniprot IDs		O95429	P41238
PDB IDs		1M62 1M7K
Enriched GO Terms of Interacting Partners?
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