SMIM3 and PMP22

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		SMIM3	PMP22
Description		small integral membrane protein 3	peripheral myelin protein 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Compact Myelin Synapse
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Chemical Synaptic Transmission Peripheral Nervous System Development Cell Death Negative Regulation Of Cell Proliferation Negative Regulation Of Neuron Projection Development Bleb Assembly Myelin Assembly Myelination
Pathways			EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)	Allergic rhinitis ( 25085501) Amyotrophic lateral sclerosis ( 29566793) Corneal structure ( 23291589) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)
Interacting Genes		10 interacting genes: ATP6V0C BSCL2 CLEC7A EMP1 LZTS2 MAL PMP22 PNMA1 SFTPC TRIM14	8 interacting genes: CANX CREB3 DDX52 KLRC1 LMNA MPZ PEX19 SMIM3
Entrez ID		85027	5376
HPRD ID		12212	03059
Ensembl ID		ENSG00000256235	ENSG00000109099
Uniprot IDs		Q9BZL3	A8MU75 Q01453 Q6FH25
PDB IDs
Enriched GO Terms of Interacting Partners?
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