PMP22 and SMIM3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		PMP22	SMIM3
Description		peripheral myelin protein 22	small integral membrane protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Compact Myelin Synapse	Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Chemical Synaptic Transmission Peripheral Nervous System Development Cell Death Negative Regulation Of Cell Proliferation Negative Regulation Of Neuron Projection Development Bleb Assembly Myelin Assembly Myelination
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Allergic rhinitis ( 25085501) Amyotrophic lateral sclerosis ( 29566793) Corneal structure ( 23291589) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)	Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)
Interacting Genes		8 interacting genes: CANX CREB3 DDX52 KLRC1 LMNA MPZ PEX19 SMIM3	10 interacting genes: ATP6V0C BSCL2 CLEC7A EMP1 LZTS2 MAL PMP22 PNMA1 SFTPC TRIM14
Entrez ID		5376	85027
HPRD ID		03059	12212
Ensembl ID		ENSG00000109099	ENSG00000256235
Uniprot IDs		A8MU75 Q01453 Q6FH25	Q9BZL3
PDB IDs
Enriched GO Terms of Interacting Partners?
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