SMIM3 and SFTPC

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		SMIM3	SFTPC
Description		small integral membrane protein 3	surfactant protein C
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Multivesicular Body Lumen
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process		Respiratory Gaseous Exchange Cellular Protein Metabolic Process
Pathways			Surfactant metabolism Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS) Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
Drugs
Diseases			Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)	Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323)
Interacting Genes		10 interacting genes: ATP6V0C BSCL2 CLEC7A EMP1 LZTS2 MAL PMP22 PNMA1 SFTPC TRIM14	12 interacting genes: CREB3 CXCL9 LMNA NEDD4 PQBP1 SEC22A SEC61G SMIM3 SYNE4 TMEM79 WWP1 WWP2
Entrez ID		85027	6440
HPRD ID		12212	01520
Ensembl ID		ENSG00000256235	ENSG00000168484
Uniprot IDs		Q9BZL3	A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686
PDB IDs			2YAD
Enriched GO Terms of Interacting Partners?
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