PPFIA1 and ERC1

Number of citations of the paper that reports this interaction (PubMedID 12923177)
60

Data Source:
HPRD (in vitro, in vivo)

		PPFIA1	ERC1
Description		PTPRF interacting protein alpha 1	ELKS/RAB6-interacting/CAST family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Axon Dendrite Protein-containing Complex Presynaptic Active Zone	Golgi Membrane Cytoplasm Centrosome IkappaB Kinase Complex Cell Junction Ciliary Basal Body Presynaptic Membrane Synapse
	Molecular Function	Protein Binding	Protein Binding Rab GTPase Binding PDZ Domain Binding Leucine Zipper Domain Binding Cadherin Binding
	Biological Process	Cell-matrix Adhesion Signal Transduction Neurotransmitter Secretion Glutamate Secretion Synapse Organization Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Localization To Plasma Membrane	Regulation Of Transcription, DNA-templated I-kappaB Phosphorylation Multicellular Organism Development Protein Transport Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Body mass index ( 26426971) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420)
Interacting Genes		26 interacting genes: AGTPBP1 CAGE1 CAST CCNH CEP70 DNAJC5 DTNB ERC1 ERC2 FAM161A GIT1 MBIP NCOA2 NDN PPFIA2 PPFIA3 PPFIBP1 PPFIBP2 PPP2R5D PTPRC PTPRD PTPRF PTPRS TNNT1 TXLNA YWHAG	19 interacting genes: APP CD163 CRIP1 DNAJC5 FGF23 FPR2 GALNT8 GPRC5D IFFO1 ITSN2 MRTFB NCAPD2 PPFIA1 PRMT8 RAB6A RAB6B RIMS1 SRPK2 YWHAG
Entrez ID		8500	23085
HPRD ID		11451	06181
Ensembl ID		ENSG00000131626	ENSG00000082805
Uniprot IDs		B3KVS8 Q13136	G8JLD3 Q8IUD2 X6RLX0
PDB IDs		1N7F
Enriched GO Terms of Interacting Partners?
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