ERC1 and PRMT8

		ERC1	PRMT8
Description		ELKS/RAB6-interacting/CAST family member 1	protein arginine methyltransferase 8
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Centrosome IkappaB Kinase Complex Cell Junction Ciliary Basal Body Presynaptic Membrane Synapse	Nucleus Plasma Membrane Anchored Component Of The Cytoplasmic Side Of The Plasma Membrane
	Molecular Function	Protein Binding Rab GTPase Binding PDZ Domain Binding Leucine Zipper Domain Binding Cadherin Binding	Protein Binding Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Enzyme Binding Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Identical Protein Binding Protein Homodimerization Activity S-adenosyl-L-methionine Binding
	Biological Process	Regulation Of Transcription, DNA-templated I-kappaB Phosphorylation Multicellular Organism Development Protein Transport Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity	Protein Methylation Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Histone Arginine Methylation Regulation Of Protein Binding Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420)	Cardiac Troponin-T levels ( 31014085) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Gut microbiota (bacterial taxa) ( 27723756) HDL cholesterol ( 19060911)
Interacting Genes		19 interacting genes: APP CD163 CRIP1 DNAJC5 FGF23 FPR2 GALNT8 GPRC5D IFFO1 ITSN2 MRTFB NCAPD2 PPFIA1 PRMT8 RAB6A RAB6B RIMS1 SRPK2 YWHAG	13 interacting genes: CEP162 COIL DCAF8 ERC1 GPATCH2L H4C1 OFCC1 PPARA PRMT1 SERBP1 TAF15 VHL ZNF451
Entrez ID		23085	56341
HPRD ID		06181	11029
Ensembl ID		ENSG00000082805	ENSG00000111218
Uniprot IDs		G8JLD3 Q8IUD2 X6RLX0	Q59GT2 Q9NR22
PDB IDs			4X41 5DST
Enriched GO Terms of Interacting Partners?
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