ERC1 and RAB6A

Number of citations of the paper that reports this interaction (PubMedID 11929610)
46

Data Source:
HPRD (two hybrid, in vitro)

		ERC1	RAB6A
Description		ELKS/RAB6-interacting/CAST family member 1	RAB6A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Centrosome IkappaB Kinase Complex Cell Junction Ciliary Basal Body Presynaptic Membrane Synapse	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle
	Molecular Function	Protein Binding Rab GTPase Binding PDZ Domain Binding Leucine Zipper Domain Binding Cadherin Binding	GTPase Activity Protein Binding GTP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Regulation Of Transcription, DNA-templated I-kappaB Phosphorylation Multicellular Organism Development Protein Transport Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Viral Process Peptidyl-cysteine Methylation Antigen Processing And Presentation Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Neutrophil Degranulation Minus-end-directed Organelle Transport Along Microtubule
Pathways			Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Body mass index ( 26426971) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420)	Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)
Interacting Genes		19 interacting genes: APP CD163 CRIP1 DNAJC5 FGF23 FPR2 GALNT8 GPRC5D IFFO1 ITSN2 MRTFB NCAPD2 PPFIA1 PRMT8 RAB6A RAB6B RIMS1 SRPK2 YWHAG	21 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1
Entrez ID		23085	5870
HPRD ID		06181	01543
Ensembl ID		ENSG00000082805	ENSG00000175582
Uniprot IDs		G8JLD3 Q8IUD2 X6RLX0	A0A024R5H8 A0A024R5J5 P20340 Q53ET8
PDB IDs			1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?
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