PPFIA2 and PPFIA3

Number of citations of the paper that reports this interaction (PubMedID 9624153)
84

Data Source:
HPRD (in vitro)

		PPFIA2	PPFIA3
Description		PTPRF interacting protein alpha 2	PTPRF interacting protein alpha 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cell Surface Cell Junction Axon Dendritic Spine Presynaptic Active Zone Extracellular Exosome Glutamatergic Synapse	Acrosomal Vesicle Cytosol Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component Epididymosome Glutamatergic Synapse
	Molecular Function	Protein Binding Structural Constituent Of Presynapse	Protein Binding
	Biological Process	Cell-matrix Adhesion Neurotransmitter Secretion Glutamate Secretion Synapse Organization Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Presynapse Organization Dense Core Granule Cytoskeletal Transport Regulation Of Synaptic Vesicle Exocytosis	Neurotransmitter Secretion Glutamate Secretion Synaptic Vesicle Docking Regulation Of Short-term Neuronal Synaptic Plasticity Synapse Organization
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Age-related cataracts (age at onset) ( 25352737) Alcohol dependence ( 26365420) Delirium ( 29631748) Lean body mass ( 28552196) Post bronchodilator FEV1 ( 26634245) Resting heart rate ( 27798624) Schizophrenia ( 22885689)
Interacting Genes		13 interacting genes: CAST CDC5L ERC2 GIT1 ITSN1 MTDH PPFIA1 PPFIA3 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS	11 interacting genes: CAST ERC2 GIT1 PPFIA1 PPFIA2 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS PTPRU
Entrez ID		8499	8541
HPRD ID		04392	04393
Ensembl ID		ENSG00000139220	ENSG00000177380
Uniprot IDs		B7Z7Y5 G3V200 H0YHK3 O75334 Q4LE62	O75145
PDB IDs		3TAC 3TAD 6IUH
Enriched GO Terms of Interacting Partners?
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