PPFIA2 and PTPRD

  • Number of citations of the paper that reports this interaction (PubMedID 9624153)
  • 84
  • Data Source:
  • HPRD (in vitro)

PPFIA2

PTPRD

Description PTPRF interacting protein alpha 2 protein tyrosine phosphatase receptor type D
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related cognitive decline (language) (slope of z-scores) ( 30954325)
  • Airflow obstruction ( 22837378)
  • Anxiety and major depressive disorder ( 24047446)
  • Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
  • Bitter alcoholic beverage consumption ( 31046077)
  • Body mass index (change over time) in gastrointestinal cancer or chronic obstructive pulmonary disease ( 28044437)
  • Cardiac Troponin-T levels ( 31014085)
  • Cerebrospinal P-tau181p levels ( 28247064)
  • Chronotype ( 30696823)
  • Diastolic blood pressure ( 30224653)
  • Early age at menarche ( 29773799)
  • Endometrial cancer (endometrioid histology) ( 30093612)
  • Endometriosis or endometrial cancer (pleiotropy) ( 29608257)
  • Epilepsy (remission after treatment) ( 23962720)
  • Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243)
  • Gait rhythm ( 26219847)
  • Glycine levels ( 31070104)
  • Gout ( 22179738)
  • Heel bone mineral density ( 30598549)
  • Immune response to measles-mumps-rubella vaccine ( 24811271)
  • Intracranial aneurysm ( 29531279)
  • Lean body mass ( 28552196)
  • Loneliness ( 27629369)
  • Loneliness (linear analysis) ( 27629369)
  • Loneliness (multivariate analysis) ( 27629369)
  • Low susceptibility to hepatitis C infection ( 31206233)
  • Menarche (age at onset) ( 29773799 25231870)
  • Metabolite levels ( 23823483)
  • Midgestational circulating levels of PCBs (fetal genetic effect) ( 28235828)
  • Moderate-to-late spontaneous preterm birth ( 31194736)
  • Modic changes ( 30808802)
  • Mood instability ( 29187730)
  • Morning person ( 30696823)
  • Myopia (pathological) ( 23049088)
  • Non-alcoholic fatty liver disease activity score ( 31311600)
  • Non-response to antidepressants and depression ( 27622933)
  • Obesity-related traits ( 23251661)
  • Obsessive-compulsive disorder ( 24821223)
  • Palmitic acid (16:0) levels ( 23362303)
  • Partial epilepsies ( 20522523)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Personality dimensions ( 23903073)
  • Pit-and-Fissure caries ( 24556642)
  • Plasma clusterin levels ( 26545630)
  • Platelet aggregation ( 20526338)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1 in COPD ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Pulse pressure ( 27841878)
  • Pursuit maintenance gain ( 29064472)
  • Resistant hypertension ( 30237584)
  • Resting-state electroencephalogram vigilance ( 29703947)
  • Restless legs syndrome ( 18660810 29029846 21779176)
  • Short-term memory (digit-span task) ( 30741946)
  • Subcutaneous adipose tissue ( 26480920)
  • Systolic blood pressure ( 30224653 27841878)
  • Temperament ( 22832960)
  • Third ventricle volume ( 31530798)
  • Type 2 diabetes ( 21647700 20174558)
  • Waist-hip ratio ( 28552196)
  • Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
  • White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes 13 interacting genes: CAST CDC5L ERC2 GIT1 ITSN1 MTDH PPFIA1 PPFIA3 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS 33 interacting genes: ABLIM1 AURKA BMX CSNK1D CSNK1E DDX17 DDX54 EPHA8 GPC4 IL1RAP IRS1 MARK2 MATK MTNR1A MTNR1B MTSS1 NEK1 NEK2 NEK6 PAK6 PLK1 PPFIA1 PPFIA2 PPFIA3 PTPRA PTPRE PTPRF PTPRS SCEL SLAIN2 SMTNL2 TBK1 TSSK2
Entrez ID 8499 5789
HPRD ID 04392 03358
Ensembl ID ENSG00000139220 ENSG00000153707
Uniprot IDs B7Z7Y5 G3V200 H0YHK3 O75334 Q4LE62 P23468 Q2HXI4 Q3KPI9 Q59H90
PDB IDs 3TAC 3TAD 6IUH 1X5Z 2DLH 2YD6 2YD7 4RCA 5WY8 5XNP
Enriched GO Terms of Interacting Partners?
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