ZGPAT and AMOTL2

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		ZGPAT	AMOTL2
Description		zinc finger CCCH-type and G-patch domain containing	angiomotin like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Plasma Membrane	Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Transcription, DNA-templated	Angiogenesis Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Wnt Signaling Pathway Actin Cytoskeleton Organization Regulation Of Cell Migration Hippo Signaling
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) C-reactive protein levels ( 30388399) Crohn's disease ( 28067908) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462) Inflammatory bowel disease ( 28067908 23128233) Lung function (FEV1) ( 28166213) Prostate cancer ( 31562322 23535732) Ulcerative colitis ( 28067908 21297633)	Cadmium levels ( 26025379) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
Interacting Genes		39 interacting genes: AIMP2 AMOTL2 BEND5 BLZF1 CCDC33 CCDC57 CCNDBP1 CDCA7L CDR2 CEP57L1 CEP70 CTNNA1 DHX15 DVL2 DYDC1 FAM9B GOLGA2 IHO1 IKZF3 KIFC3 KRT15 KRT40 LDOC1 LZTS2 MID2 MIPOL1 NEBL PHC2 PRPF3 SPAG5 SSX2IP STAC3 TFIP11 TLE5 TP53BP2 TRIM27 TRIM54 UPF2 ZBTB8A	57 interacting genes: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CHCHD3 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FBXO7 FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MTNR1A MYO5B NDC80 NFIL3 NTAQ1 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPOP SPP1 THRA TMCC2 TNKS2 TRAF2 TRIM27 ZBED1 ZGPAT
Entrez ID		84619	51421
HPRD ID		15736	16485
Ensembl ID		ENSG00000197114	ENSG00000114019
Uniprot IDs		A0A0S2Z5X3 Q8N5A5	Q9Y2J4
PDB IDs		4II1
Enriched GO Terms of Interacting Partners?
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