AMOTL2 and SH3RF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AMOTL2	SH3RF2
Description		angiomotin like 2	SH3 domain containing ring finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Phosphatase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Angiogenesis Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Wnt Signaling Pathway Actin Cytoskeleton Organization Regulation Of Cell Migration Hippo Signaling	Negative Regulation Of Phosphatase Activity Positive Regulation Of Cell Migration Negative Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Apoptotic Process Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade Protein Autoubiquitination
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS		Cadmium levels ( 26025379) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)	Bacteremia ( 27236921) Response to (pegylated) interferon in HBeAG-positive hepatitis B ( 30715261)
Interacting Genes		57 interacting genes: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CHCHD3 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FBXO7 FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MTNR1A MYO5B NDC80 NFIL3 NTAQ1 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPOP SPP1 THRA TMCC2 TNKS2 TRAF2 TRIM27 ZBED1 ZGPAT	15 interacting genes: AMOTL2 APP BANP CBY2 FASLG GOLGA2 HOMEZ LMNA LZTS2 MTUS2 PAK4 PPP1CA PPP1CC RBPMS UBE2N
Entrez ID		51421	153769
HPRD ID		16485	10229
Ensembl ID		ENSG00000114019	ENSG00000156463
Uniprot IDs		Q9Y2J4	Q08AM8 Q8TEC5
PDB IDs
Enriched GO Terms of Interacting Partners?
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