ZGPAT and NEBL

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		ZGPAT	NEBL
Description		zinc finger CCCH-type and G-patch domain containing	nebulette
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Plasma Membrane	Stress Fiber Z Disc I Band Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding Tropomyosin Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Filamin Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Transcription, DNA-templated	Muscle Fiber Development Cardiac Muscle Thin Filament Assembly
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) C-reactive protein levels ( 30388399) Crohn's disease ( 28067908) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462) Inflammatory bowel disease ( 28067908 23128233) Lung function (FEV1) ( 28166213) Prostate cancer ( 31562322 23535732) Ulcerative colitis ( 28067908 21297633)	Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Atrial fibrillation ( 28416822) Coronary artery aneurysm in Kawasaki disease ( 27171184) Heel bone mineral density ( 30598549) Liver injury in combined anti-retroviral and anti-tuberculosis drug-treated HIV with tuberculosis ( 28388302) Metabolite levels ( 23823483) Ovarian cancer ( 23535730) Photic sneeze reflex ( 27182965) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Plasma anti-thyroid peroxidase levels ( 29678681) Pulse pressure ( 27841878) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Sporadic pituitary adenoma ( 26029870) Urate levels in lean individuals ( 25811787) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference ( 28552196)
Interacting Genes		39 interacting genes: AIMP2 AMOTL2 BEND5 BLZF1 CCDC33 CCDC57 CCNDBP1 CDCA7L CDR2 CEP57L1 CEP70 CTNNA1 DHX15 DVL2 DYDC1 FAM9B GOLGA2 IHO1 IKZF3 KIFC3 KRT15 KRT40 LDOC1 LZTS2 MID2 MIPOL1 NEBL PHC2 PRPF3 SPAG5 SSX2IP STAC3 TFIP11 TLE5 TP53BP2 TRIM27 TRIM54 UPF2 ZBTB8A	24 interacting genes: ACTB ACTN1 ACTN3 CCDC136 FAM9B GMCL1 GOLGA2 HOMER3 LZTS2 MAD1L1 MIPOL1 MYPN NUTM1 PRKAB2 TRAF1 TRAF2 TRIM27 TRIM55 TRIM63 XIRP1 XIRP2 ZDHHC17 ZGPAT ZYX
Entrez ID		84619	10529
HPRD ID		15736	10403
Ensembl ID		ENSG00000197114	ENSG00000078114
Uniprot IDs		A0A0S2Z5X3 Q8N5A5	O76041 Q59FZ8
PDB IDs		4II1	4F14
Enriched GO Terms of Interacting Partners?
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