TRAPPC9 and TRAPPC2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology, genetic interference, two hybrid)

		TRAPPC9	TRAPPC2
Description		trafficking protein particle complex 9	trafficking protein particle complex 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Trans-Golgi Network Cytosol TRAPP Complex	Golgi Membrane Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Transcription Factor Binding Ion Channel Binding
	Biological Process	Cerebral Cortex Development Neuron Differentiation COPII Vesicle Coating Positive Regulation Of NF-kappaB Transcription Factor Activity	Skeletal System Development Regulation Of Transcription, DNA-templated ER To Golgi Vesicle-mediated Transport COPII Vesicle Coating
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Nonsyndromic autosomal recessive mental retardation (NS-ARMR)	Spondyloepiphyseal dysplasia tarda
GWAS		Blood pressure (smoking interaction) ( 25189868) Diastolic blood pressure ( 30578418) Disease progression in age-related macular degeneration ( 29346644) Emphysema distribution in smoking ( 27669027) Hip circumference adjusted for BMI ( 28552196) Major depressive disorder ( 29317602) Obesity-related traits ( 23251661) Pars opercularis volume ( 31530798) Pediatric non-alcoholic fatty liver disease activity score ( 28918882) Pulse pressure ( 28135244 27841878 28739976 30578418) Response to (pegylated) interferon in chronic hepatitis B ( 30715261) Response to amphetamines ( 22952603) Systolic blood pressure ( 27841878)
Interacting Genes		5 interacting genes: APP TRAPPC12 TRAPPC2 TRAPPC3L TRAPPC8	14 interacting genes: CLIC1 CLIC2 DAPK1 ENO1 MFHAS1 NR5A1 PITX1 TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9
Entrez ID		83696	6399
HPRD ID		18136	02189
Ensembl ID		ENSG00000167632	ENSG00000196459
Uniprot IDs		Q96Q05	P0DI81 P0DI82 Q6IBE5
PDB IDs
Enriched GO Terms of Interacting Partners?
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