TRAPPC9 and TRAPPC12

Number of citations of the paper that reports this interaction (PubMedID 21525244)
44

Data Source:
BioGRID (two hybrid)

		TRAPPC9	TRAPPC12
Description		trafficking protein particle complex 9	trafficking protein particle complex 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Trans-Golgi Network Cytosol TRAPP Complex	Kinetochore Cell Nucleus Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Endopeptidase Activity Protein Binding
	Biological Process	Cerebral Cortex Development Neuron Differentiation COPII Vesicle Coating Positive Regulation Of NF-kappaB Transcription Factor Activity	Proteolysis ER To Golgi Vesicle-mediated Transport Golgi Organization Metaphase Plate Congression Regulation Of Kinetochore Assembly Positive Regulation Of Protein Localization To Kinetochore
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
GWAS		Blood pressure (smoking interaction) ( 25189868) Diastolic blood pressure ( 30578418) Disease progression in age-related macular degeneration ( 29346644) Emphysema distribution in smoking ( 27669027) Hip circumference adjusted for BMI ( 28552196) Major depressive disorder ( 29317602) Obesity-related traits ( 23251661) Pars opercularis volume ( 31530798) Pediatric non-alcoholic fatty liver disease activity score ( 28918882) Pulse pressure ( 28135244 27841878 28739976 30578418) Response to (pegylated) interferon in chronic hepatitis B ( 30715261) Response to amphetamines ( 22952603) Systolic blood pressure ( 27841878)	Neuritic plaques or neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy) ( 29458411)
Interacting Genes		5 interacting genes: APP TRAPPC12 TRAPPC2 TRAPPC3L TRAPPC8	9 interacting genes: FBXO7 MTDH TFCP2 TRAPPC10 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9
Entrez ID		83696	51112
HPRD ID		18136	15580
Ensembl ID		ENSG00000167632	ENSG00000171853
Uniprot IDs		Q96Q05	A0A0J9YXQ9 Q8WVT3
PDB IDs
Enriched GO Terms of Interacting Partners?
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