TRAPPC2 and PITX1

Number of citations of the paper that reports this interaction (PubMedID 20498720)
11

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		TRAPPC2	PITX1
Description		trafficking protein particle complex 2	paired like homeodomain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Nuclear Chromatin Nucleus Transcription Factor Complex Cytoplasm
	Molecular Function	Protein Binding Transcription Factor Binding Ion Channel Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Skeletal System Development Regulation Of Transcription, DNA-templated ER To Golgi Vesicle-mediated Transport COPII Vesicle Coating	Skeletal System Development Anatomical Structure Morphogenesis Branchiomeric Skeletal Muscle Development Pituitary Gland Development Embryonic Hindlimb Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Myoblast Fate Commitment Cartilage Development
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Spondyloepiphyseal dysplasia tarda	Congenital clubfoot; Congenital talipes equinovarus
GWAS			Atrial fibrillation ( 29237688) Bulimia nervosa ( 23568457) Colorectal cancer ( 30529582 24836286 23263487) Colorectal cancer or advanced adenoma ( 30510241) Height ( 20881960 25429064 23563607 31562340 18391951) Immune response to anthrax vaccine ( 22658931) Testicular germ cell tumor ( 28604732 23666240)
Interacting Genes		14 interacting genes: CLIC1 CLIC2 DAPK1 ENO1 MFHAS1 NR5A1 PITX1 TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9	27 interacting genes: ALG13 C1orf94 CDX4 DVL3 EGR1 FOXO1 GOLGA2 HGS IPO13 LZTS2 MAGED1 MGAT5B NEUROD1 NR5A1 PLSCR1 POU1F1 PRR20A RBPMS RFX6 RHOXF2 RNF31 SMARCA2 SPAG8 TRAPPC2 TRIM23 UPF2 ZBTB32
Entrez ID		6399	5307
HPRD ID		02189	03688
Ensembl ID		ENSG00000196459	ENSG00000069011
Uniprot IDs		P0DI81 P0DI82 Q6IBE5	P78337 X5D9A5
PDB IDs
Enriched GO Terms of Interacting Partners?
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