STAM and TRIM55

Number of citations of the paper that reports this interaction (PubMedID 22626734)
5

Data Source:
BioGRID (enzymatic study)

		STAM	TRIM55
Description		signal transducing adaptor molecule	tripartite motif containing 55
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Early Endosome Membrane ESCRT-0 Complex	Nucleus Cytoplasm Microtubule
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding Ubiquitin-like Protein Ligase Binding	Protein Binding Zinc Ion Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Signal Transduction Positive Regulation Of Signal Transduction Endosomal Transport Macroautophagy Protein Deubiquitination Multivesicular Body Assembly Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Exosome Assembly	Signal Transduction
Pathways		EGFR downregulation Metalloprotease DUBs Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS			Coronary heart disease event reduction (statin therapy interaction) ( 22666496) Metabolite levels ( 23823483) Recurrent major depressive disorder ( 29317602)
Interacting Genes		20 interacting genes: ARRB1 HGS JAK1 JAK2 JAK3 MAP3K1 PJA1 PMEPA1 PPP1CA PPP1CC RFFL STAMBP TIMM8A TRIM54 TRIM55 TRIM63 UBC USP15 USP28 USP8	62 interacting genes: ACTA1 ANKRD1 ATP5F1B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UBE2L3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1
Entrez ID		8027	84675
HPRD ID		03542	05927
Ensembl ID		ENSG00000136738	ENSG00000147573
Uniprot IDs		B4DZT2 Q92783	Q9BYV6
PDB IDs		2L0A 3F1I 3LDZ
Enriched GO Terms of Interacting Partners?
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