C1orf50 and AHCY

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology)

		C1orf50	AHCY
Description		chromosome 1 open reading frame 50	adenosylhomocysteinase
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytosol Melanosome Neuron Projection Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Adenosylhomocysteinase Activity Protein Binding Adenyl Nucleotide Binding Identical Protein Binding NAD Binding
	Biological Process		Sulfur Amino Acid Metabolic Process Response To Hypoxia Chronic Inflammatory Response To Antigenic Stimulus One-carbon Metabolic Process Response To Nutrient S-adenosylhomocysteine Catabolic Process Methylation S-adenosylmethionine Cycle Circadian Sleep/wake Cycle
Pathways			Methylation Sulfur amino acid metabolism Metabolism of ingested SeMet, Sec, MeSec into H2Se Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Drugs			Isopropyl Alcohol (1'r,2's)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-Yl)Adenine 3'-Oxo-Adenosine D-Eritadenine Copper
Diseases			Hypermethioninemia; Methionine adenosyltransferase deficiency; S-adenosylhomocysteine hydrolase deficiency
GWAS			Heel bone mineral density ( 30598549) Height ( 28552196) Vitiligo ( 27723757)
Interacting Genes		8 interacting genes: AHCY APPBP2 CLSPN EPM2AIP1 EXO5 NTAQ1 PPCS ZMYND12	7 interacting genes: ANKRD40 APPBP2 C1orf50 POT1 PXN TERF1 YWHAQ
Entrez ID		79078	191
HPRD ID		14714	01621
Ensembl ID		ENSG00000164008	ENSG00000101444
Uniprot IDs		Q9BV19	A0A384MTQ3 P23526 Q1RMG2
PDB IDs			1A7A 1LI4 3NJ4 4PFJ 4PGF 4YVF 5W49 5W4B
Enriched GO Terms of Interacting Partners?
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