AHCY and ANKRD40

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology)

		AHCY	ANKRD40
Description		adenosylhomocysteinase	ankyrin repeat domain 40
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Melanosome Neuron Projection Extracellular Exosome	Cellular_component
	Molecular Function	Adenosylhomocysteinase Activity Protein Binding Adenyl Nucleotide Binding Identical Protein Binding NAD Binding	Molecular_function Protein Binding
	Biological Process	Sulfur Amino Acid Metabolic Process Response To Hypoxia Chronic Inflammatory Response To Antigenic Stimulus One-carbon Metabolic Process Response To Nutrient S-adenosylhomocysteine Catabolic Process Methylation S-adenosylmethionine Cycle Circadian Sleep/wake Cycle	Biological_process
Pathways		Methylation Sulfur amino acid metabolism Metabolism of ingested SeMet, Sec, MeSec into H2Se Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Drugs		Isopropyl Alcohol (1'r,2's)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-Yl)Adenine 3'-Oxo-Adenosine D-Eritadenine Copper
Diseases		Hypermethioninemia; Methionine adenosyltransferase deficiency; S-adenosylhomocysteine hydrolase deficiency
GWAS		Heel bone mineral density ( 30598549) Height ( 28552196) Vitiligo ( 27723757)
Interacting Genes		7 interacting genes: ANKRD40 APPBP2 C1orf50 POT1 PXN TERF1 YWHAQ	4 interacting genes: AHCY PIN1 RAD23A SDCBP
Entrez ID		191	91369
HPRD ID		01621	17502
Ensembl ID		ENSG00000101444	ENSG00000154945
Uniprot IDs		A0A384MTQ3 P23526 Q1RMG2	A8IK34 Q6AI12
PDB IDs		1A7A 1LI4 3NJ4 4PFJ 4PGF 4YVF 5W49 5W4B
Enriched GO Terms of Interacting Partners?
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