AHCY and C1orf50

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology)

		AHCY	C1orf50
Description		adenosylhomocysteinase	chromosome 1 open reading frame 50
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Melanosome Neuron Projection Extracellular Exosome
	Molecular Function	Adenosylhomocysteinase Activity Protein Binding Adenyl Nucleotide Binding Identical Protein Binding NAD Binding	Protein Binding Identical Protein Binding
	Biological Process	Sulfur Amino Acid Metabolic Process Response To Hypoxia Chronic Inflammatory Response To Antigenic Stimulus One-carbon Metabolic Process Response To Nutrient S-adenosylhomocysteine Catabolic Process Methylation S-adenosylmethionine Cycle Circadian Sleep/wake Cycle
Pathways		Methylation Sulfur amino acid metabolism Metabolism of ingested SeMet, Sec, MeSec into H2Se Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Drugs		Isopropyl Alcohol (1'r,2's)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-Yl)Adenine 3'-Oxo-Adenosine D-Eritadenine Copper
Diseases		Hypermethioninemia; Methionine adenosyltransferase deficiency; S-adenosylhomocysteine hydrolase deficiency
GWAS		Heel bone mineral density ( 30598549) Height ( 28552196) Vitiligo ( 27723757)
Interacting Genes		7 interacting genes: ANKRD40 APPBP2 C1orf50 POT1 PXN TERF1 YWHAQ	8 interacting genes: AHCY APPBP2 CLSPN EPM2AIP1 EXO5 NTAQ1 PPCS ZMYND12
Entrez ID		191	79078
HPRD ID		01621	14714
Ensembl ID		ENSG00000101444	ENSG00000164008
Uniprot IDs		A0A384MTQ3 P23526 Q1RMG2	Q9BV19
PDB IDs		1A7A 1LI4 3NJ4 4PFJ 4PGF 4YVF 5W49 5W4B
Enriched GO Terms of Interacting Partners?
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