LAPTM5 and HERC1

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
HPRD (two hybrid)

		LAPTM5	HERC1
Description		lysosomal protein transmembrane 5	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Integral Component Of Plasma Membrane Membrane	Cytoplasm Golgi Apparatus Cytosol Membrane
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity ARF Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Cellular Response To Leukemia Inhibitory Factor	Negative Regulation Of Autophagy Protein Ubiquitination Cerebellar Purkinje Cell Differentiation Corpus Callosum Development Neuron Projection Development Neuromuscular Process Controlling Balance
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369)	Atrial fibrillation ( 30061737) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Glucagon levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Iris characteristics ( 21835309) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		25 interacting genes: ANKRD13A DCUN1D1 DISP1 EPN1 EPN2 EPN3 EPS15 HERC1 HEY1 HEYL HUWE1 ITCH KRT7 LDLRAD1 NEDD4 NEDD4L RNF168 SMURF2 TNFAIP3 TOM1L2 UBA52 UBAC1 UBC USP13 WWP1	12 interacting genes: BAK1 EP300 LAPTM5 PKM RAF1 RNF11 SOX9 UBC UBE2D2 UBE2D3 UBE2L3 UBE2S
Entrez ID		7805	8925
HPRD ID		03280	06894
Ensembl ID		ENSG00000162511	ENSG00000103657
Uniprot IDs		Q13571 Q5TBB8	A0A024R5W0 Q15751
PDB IDs			4O2W 4QT6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?