LAPTM5 and EPN1

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LAPTM5	EPN1
Description		lysosomal protein transmembrane 5	epsin 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Integral Component Of Plasma Membrane Membrane	Nucleus Cytosol Plasma Membrane Clathrin-coated Pit
	Molecular Function	Protein Binding	Protein Binding Lipid Binding
	Biological Process	Cellular Response To Leukemia Inhibitory Factor	In Utero Embryonic Development Endocytosis Notch Signaling Pathway Female Pregnancy Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Embryonic Organ Development Membrane Organization Negative Regulation Of Sprouting Angiogenesis
Pathways			EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs			1,4-Diethylene Dioxide 1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS		Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369)	Major depressive disorder ( 23377640)
Interacting Genes		25 interacting genes: ANKRD13A DCUN1D1 DISP1 EPN1 EPN2 EPN3 EPS15 HERC1 HEY1 HEYL HUWE1 ITCH KRT7 LDLRAD1 NEDD4 NEDD4L RNF168 SMURF2 TNFAIP3 TOM1L2 UBA52 UBAC1 UBC USP13 WWP1	24 interacting genes: AP2A1 AP2A2 CDK1 CEP126 CLTC CRMP1 DAZAP2 EPS15 EPS15L1 FBXO25 HIP1R LAPTM5 MAP3K1 MED31 PLEKHB2 REPS2 RNF11 SCNN1A SCNN1B SCNN1G SMURF1 TFAP2A UBC ZBTB16
Entrez ID		7805	29924
HPRD ID		03280	06270
Ensembl ID		ENSG00000162511	ENSG00000063245
Uniprot IDs		Q13571 Q5TBB8	A0A024R4S1 Q9Y6I3
PDB IDs			1INZ 1KYD
Enriched GO Terms of Interacting Partners?
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