UBTF and IRS2

  • Number of citations of the paper that reports this interaction (PubMedID 12554758)
  • 26
  • Data Source:
  • HPRD (in vivo)

UBTF

IRS2

Description upstream binding transcription factor insulin receptor substrate 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Diverticular disease ( 30177863)
  • Mean corpuscular hemoglobin concentration ( 29403010)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes 33 interacting genes: AURKA CCNA2 CCND1 CCNE1 CD3EAP CDK2 CDK4 CENPC CHGB CREBBP CSNK2A1 EP300 IRS1 IRS2 LEF1 MAD1L1 MAPK1 MAPK3 MDM2 POLR1E RB1 RBL2 RUNX2 SERPINH1 SMURF1 TAF1 TAF1A TAF1B TAF1C TAF1D TBP TCOF1 ZMYM2 40 interacting genes: ATP2A1 ATP2A2 BCL2L1 CRK EPOR FES GRB2 IGF1R IL4R INSR JAK1 JAK2 JAK3 MPL MTDH NEDD4 NTRK1 PIK3CA PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PTPN11 PTPN6 PTPRF RPTOR SHC1 SOCS1 SOCS3 SOCS6 SOCS7 SRPK2 TYK2 UBTF YWHAB YWHAE YWHAG YWHAQ YWHAZ
Entrez ID 7343 8660
HPRD ID 02814 02878
Ensembl ID ENSG00000108312 ENSG00000185950
Uniprot IDs P17480 Q9P084 Q9Y4H2
PDB IDs 1K99 1L8Y 1L8Z 2HDZ 3FQW 3FQX
Enriched GO Terms of Interacting Partners?
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