IRS2 and PIK3R3

  • Number of citations of the paper that reports this interaction (PubMedID 10417350)
  • 2
  • Data Source:
  • HPRD (in vitro)

IRS2

PIK3R3

Description insulin receptor substrate 2 phosphoinositide-3-kinase regulatory subunit 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 40 interacting genes: ATP2A1 ATP2A2 BCL2L1 CRK EPOR FES GRB2 IGF1R IL4R INSR JAK1 JAK2 JAK3 MPL MTDH NEDD4 NTRK1 PIK3CA PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PTPN11 PTPN6 PTPRF RPTOR SHC1 SOCS1 SOCS3 SOCS6 SOCS7 SRPK2 TYK2 UBTF YWHAB YWHAE YWHAG YWHAQ YWHAZ 81 interacting genes: ABCB6 ABL2 AMBP ANKS1A AUNIP AXL BRK1 BTK CAMK1 CCDC14 CCDC33 CEP126 CEP19 CLNK CRBN CRK DARS1 DCAF8 DRAP1 DSN1 E2F6 EGFR ERBB2 ERBB3 ESR1 FBN3 FER FGB FOXO1 FSD2 FYN GC HROB HSH2D IGF1R INSR IQUB IRS1 IRS2 KARS1 KHDRBS1 KLC2 KLF15 KMT2B L3MBTL3 LNX2 LUC7L2 MBIP MECOM MICAL1 MTF2 NCK1 ORM1 PACRGL PCDHB5 PDGFRB PELO PIK3CA PLB1 PPARA PSME1 QARS1 RB1 RING1 SERF1A SOCS6 SRC STAT3 TEC TERF2 TNNC2 TRIM54 TRMT2A TSPAN2 USP2 VBP1 VCP WRNIP1 ZMAT1 ZNF281 ZNF451
Entrez ID 8660 8503
HPRD ID 02878 05831
Ensembl ID ENSG00000185950 ENSG00000117461
Uniprot IDs Q9P084 Q9Y4H2 B4DXM8 Q68CY7 Q7Z3W2 Q8N381 Q92569
PDB IDs 3FQW 3FQX
Enriched GO Terms of Interacting Partners?
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