UBTF and CD3EAP

Number of citations of the paper that reports this interaction (PubMedID 9426281)
12

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		UBTF	CD3EAP
Description		upstream binding transcription factor	CD3e molecule associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus	RNA Polymerase I Transcription Factor Complex Fibrillar Center Nucleoplasm Chromosome Nucleolus RNA Polymerase I Complex Mitochondrion Cytosol
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase I CORE Element Sequence-specific DNA Binding RNA Polymerase I Upstream Control Element Sequence-specific DNA Binding Chromatin Binding RNA Binding Protein Binding Scaffold Protein Binding	RNA Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly Regulation Of Transcription By RNA Polymerase I Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase I Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Positive Regulation Of Transcription By RNA Polymerase I Regulation Of Glucose Mediated Signaling Pathway	Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway RRNA Transcription Nucleolar Large RRNA Transcription By RNA Polymerase I Positive Regulation Of Gene Expression, Epigenetic
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Promoter Opening RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Diverticular disease ( 30177863) Mean corpuscular hemoglobin concentration ( 29403010) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
Interacting Genes		33 interacting genes: AURKA CCNA2 CCND1 CCNE1 CD3EAP CDK2 CDK4 CENPC CHGB CREBBP CSNK2A1 EP300 IRS1 IRS2 LEF1 MAD1L1 MAPK1 MAPK3 MDM2 POLR1E RB1 RBL2 RUNX2 SERPINH1 SMURF1 TAF1 TAF1A TAF1B TAF1C TAF1D TBP TCOF1 ZMYM2	8 interacting genes: CD3E NCL NFKBIB POLR1C POLR1D POLR1E TAF1A UBTF
Entrez ID		7343	10849
HPRD ID		02814	00125
Ensembl ID		ENSG00000108312	ENSG00000117877
Uniprot IDs		P17480	O15446
PDB IDs		1K99 1L8Y 1L8Z 2HDZ
Enriched GO Terms of Interacting Partners?
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