CD3EAP and NFKBIB

Number of citations of the paper that reports this interaction (PubMedID 14743216)
300

Data Source:
HPRD (in vitro)

		CD3EAP	NFKBIB
Description		CD3e molecule associated protein	NFKB inhibitor beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	RNA Polymerase I Transcription Factor Complex Fibrillar Center Nucleoplasm Chromosome Nucleolus RNA Polymerase I Complex Mitochondrion Cytosol	Nucleus Cytosol
	Molecular Function	RNA Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway RRNA Transcription Nucleolar Large RRNA Transcription By RNA Polymerase I Positive Regulation Of Gene Expression, Epigenetic	Transcription, DNA-templated Signal Transduction Cellular Response To Lipopolysaccharide Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	Activation of NF-kappaB in B cells RIP-mediated NFkB activation via ZBP1 TAK1 activates NFkB by phosphorylation and activation of IKKs complex TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
Interacting Genes		8 interacting genes: CD3E NCL NFKBIB POLR1C POLR1D POLR1E TAF1A UBTF	41 interacting genes: APP BAK1 BTRC CD3EAP CDC25A CHUK CSNK2A1 CUL1 DNAJA3 ESR2 FHL3 GIT2 IKBKB IKBKG KPNA2 LRPPRC MCC MTIF2 NCOR2 NFKB1 NFKB2 NFKBIA NGFR NKIRAS1 NKIRAS2 PDCD2 POLR1A POLR1B POLR1C POLR1D POLR1E POLR2H POLR2L PPARG RASAL2 REL RELA RXRA SKP1 TSPAN1 VPS52
Entrez ID		10849	4793
HPRD ID		00125	07260
Ensembl ID		ENSG00000117877	ENSG00000104825
Uniprot IDs		O15446	G5E9C2 Q15653
PDB IDs
Enriched GO Terms of Interacting Partners?
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