SF3A3 and ADAP1

Number of citations of the paper that reports this interaction (PubMedID 12565890)
4

Data Source:
HPRD (in vitro)

		SF3A3	ADAP1
Description		splicing factor 3a subunit 3	ArfGAP with dual PH domains 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing U2-type Prespliceosome Assembly	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of GTPase Activity
Pathways		mRNA Splicing - Major Pathway	Nuclear signaling by ERBB4
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Coronary artery disease ( 29212778) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Pulse pressure ( 28135244) Systolic blood pressure ( 30578418)
Interacting Genes		18 interacting genes: ADAP1 APBB1 APP CCDC85B HSPB1 MTNR1B PRMT5 PRPF40A SF3A1 SREK1 TADA2A TCERG1 TRIM69 U2AF1 VAV2 WBP4 ZDHHC17 ZNF212	23 interacting genes: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1
Entrez ID		10946	11033
HPRD ID		10411	09733
Ensembl ID		ENSG00000183431	ENSG00000105963
Uniprot IDs		B4DW90 Q12874	A8K3A2 B4DUZ7 O75689
PDB IDs		2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9	3FEH 3FM8 3LJU 3MDB
Enriched GO Terms of Interacting Partners?
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