TOP1 and FSHR

  • Number of citations of the paper that reports this interaction (PubMedID 15196694)
  • 17

TOP1

FSHR

Description DNA topoisomerase I follicle stimulating hormone receptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
  • Antipsychotic drug-induced weight gain in schizophrenia ( 31447353)
  • Cholesterol, total ( 24097068 20686565)
  • LDL cholesterol ( 24097068 20686565)
  • LDL cholesterol levels ( 28334899)
  • LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Male-pattern baldness ( 28196072)
  • Metabolite levels ( 23823483)
  • Total cholesterol levels ( 28334899)
  • Urate levels ( 31578528)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide) ( 23648065)
  • Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877)
  • Cerebrospinal fluid t-tau levels in normal cognition ( 29274321)
  • Chronotype ( 30696823)
  • Depressive symptoms (SSRI exposure interaction) ( 25649181)
  • Erectile dysfunction and prostate cancer treatment ( 20932654)
  • Laterality in neovascular age-related macular degeneration ( 28775256)
  • Lean body mass ( 28552196)
  • Low density lipoprotein cholesterol levels ( 30498476)
  • Lung cancer in ever smokers ( 28604730)
  • Metabolite levels ( 23823483)
  • Morning person ( 30696823)
  • Plasma anti-thyroglobulin levels ( 29678681)
  • Polycystic ovary syndrome ( 22885925 21151128)
  • Radiation response ( 20923822)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
Interacting Genes 59 interacting genes: APAF1 APP ATM BARD1 BRCA1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PRKDC PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRPK2 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I XRCC5 XRCC6 20 interacting genes: AKT2 APPL1 ARR3 CANX CBX5 CGA FSHB GRK2 GRK4 GRK6 MT-RNR2 RPS27A S100A10 TOP1 TUG1 UBA52 UBB UBC YWHAQ ZBTB16
Entrez ID 7150 2492
HPRD ID 00535 00639
Ensembl ID ENSG00000198900 ENSG00000170820
Uniprot IDs P11387 Q9BVT2 A0A1D5RMN4 P23945
PDB IDs 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8 1XUN 1XWD 4AY9 4MQW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?