TEAD4 and HOMEZ

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		TEAD4	HOMEZ
Description		TEA domain transcription factor 4	homeobox and leucine zipper encoding
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity
	Biological Process	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Muscle Organ Development Hippo Signaling Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription
Drugs
Diseases
GWAS		Narcolepsy with cataplexy ( 23496005)	Height ( 31562340) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		29 interacting genes: CCDC172 CCDC85B CCNDBP1 CEP55 CEP70 CTBP1 EXOC3-AS1 FBXO7 GOLGA2 HOMEZ KIAA0753 KRT40 KRTAP10-3 LZTS2 MDFI MTUS2 MYH7 PDE4DIP PFKM PNMA1 RABGEF1 RUNDC3A SSX2IP TRAF1 TRIM27 VGLL1 VPS52 WWTR1 YAP1	37 interacting genes: AEN AXIN1 CENPS DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 ELOA GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK1 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPGR RPL9 SDCBP SH3RF2 SMARCB1 SMYD1 SNRPB2 SUMO2 TEAD4 TLE5 TRAF4 ZBTB7A ZNF688
Entrez ID		7004	57594
HPRD ID		03421	12167
Ensembl ID		ENSG00000197905	ENSG00000215271
Uniprot IDs		Q15561	Q8IX15
PDB IDs		5GZB 5NO6 5OAQ 6GE3 6GE4 6GE5 6GE6 6GEC 6GEE 6GEG 6GEI 6GEK 6HIK 6Q2X 6Q36 6SEN 6SEO	2ECC 2YS9
Enriched GO Terms of Interacting Partners?
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