HOMEZ and AEN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HOMEZ	AEN
Description		homeobox and leucine zipper encoding	apoptosis enhancing nuclease
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol	Nucleus Nucleoplasm Nucleolus Nuclear Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity	Nucleic Acid Binding Exonuclease Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	DNA Catabolic Process, Exonucleolytic RNA Catabolic Process Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Viral Genome Replication Defense Response To Virus
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)
Interacting Genes		37 interacting genes: AEN AXIN1 CENPS DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 ELOA GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK1 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPGR RPL9 SDCBP SH3RF2 SMARCB1 SMYD1 SNRPB2 SUMO2 TEAD4 TLE5 TRAF4 ZBTB7A ZNF688	34 interacting genes: CRTC3 EMD EXOSC8 GNPTAB HOMEZ IKZF1 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF473
Entrez ID		57594	64782
HPRD ID		12167	08573
Ensembl ID		ENSG00000215271	ENSG00000181026
Uniprot IDs		Q8IX15	Q8WTP8
PDB IDs		2ECC 2YS9
Enriched GO Terms of Interacting Partners?
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