TACC1 and SH2D4A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TACC1	SH2D4A
Description		transforming acidic coiled-coil containing protein 1	SH2 domain containing 4A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Membrane Midbody	Cytoplasm Cytosol
	Molecular Function	Protein Binding Nuclear Receptor Binding Estrogen Receptor Binding Glucocorticoid Receptor Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding	Protein Binding Phosphatase Binding Signaling Adaptor Activity
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Proliferation Cerebral Cortex Development Cell Division Positive Regulation Of Nuclear Receptor Transcription Coactivator Activity	Positive Regulation Of Signal Transduction Negative Regulation Of Phosphatase Activity
Pathways
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)	Smooth-surface caries ( 24556642) Urate levels in overweight individuals ( 25811787) Urinary albumin excretion rate in type 1 diabetes ( 24595857)
Interacting Genes		15 interacting genes: AURKA AURKB BTRC HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 YEATS4	44 interacting genes: ALAS1 CASK CCDC172 CDR2 CEP70 CEP76 DBNL FSD2 GOLGA2 GRB2 HCLS1 HMBOX1 IKZF1 KRT40 LDOC1 LZTS2 MAGEA11 MAGEA6 MTUS2 NECAB2 NINL NUTM1 OLIG1 PDE4DIP PNMA1 PPP1CB PSTPIP1 RINT1 SH3GL1 SKAP1 SORBS2 SORBS3 SPAG5 STAM2 STX11 TACC1 TFIP11 TRAF2 TRIM23 TRIM27 UBXN11 USHBP1 VPS52 ZBTB16
Entrez ID		6867	63898
HPRD ID		10391	08340
Ensembl ID		ENSG00000147526	ENSG00000104611
Uniprot IDs		E7EVI4 O75410 Q5HYH0	Q9H788
PDB IDs
Enriched GO Terms of Interacting Partners?
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