HSPA13 and UBQLN2

Number of citations of the paper that reports this interaction (PubMedID 10675567)
35

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, two hybrid)

		HSPA13	UBQLN2
Description		heat shock protein family A (Hsp70) member 13	ubiquilin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleus Cytoplasm Autophagosome Cytosol Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding ATPase Activity, Coupled Protein Binding Involved In Protein Folding Unfolded Protein Binding Misfolded Protein Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Response To Unfolded Protein Vesicle-mediated Transport Cellular Response To Unfolded Protein Protein Refolding Chaperone Cofactor-dependent Protein Refolding	Autophagosome Assembly Ubiquitin-dependent Protein Catabolic Process Regulation Of Macroautophagy Ubiquitin-dependent ERAD Pathway Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Autophagosome Assembly
Pathways		Regulation of HSF1-mediated heat shock response	Cargo recognition for clathrin-mediated endocytosis
Drugs		Copper
Diseases
GWAS
Interacting Genes		8 interacting genes: BAG6 POLE4 RMI1 SGTA SSR1 UBQLN1 UBQLN2 UBQLN4	22 interacting genes: ADRM1 ATXN7 BTRC C1QA CD93 FBXO25 FUS HERC3 HERPUD1 HNRNPA3 HSPA13 MTNR1B PRPF40A PSMA2 PSMA5 PSMD4 RNF11 RPN1 SMURF1 UBC UBE3A UBQLN4
Entrez ID		6782	29978
HPRD ID		03061	02224
Ensembl ID		ENSG00000155304	ENSG00000188021
Uniprot IDs		A0A140VK72 P48723	Q9UHD9
PDB IDs			1J8C 2NBV 6MUN
Enriched GO Terms of Interacting Partners?
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