UBQLN2 and CD93

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		UBQLN2	CD93
Description		ubiquilin 2	CD93 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Autophagosome Cytosol Plasma Membrane Cytoplasmic Vesicle	Plasma Membrane Cell Surface Integral Component Of Membrane Secretory Granule Membrane Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding Polyubiquitin Modification-dependent Protein Binding	Complement Component C1q Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Signaling Receptor Activity Transforming Growth Factor Beta Binding
	Biological Process	Autophagosome Assembly Ubiquitin-dependent Protein Catabolic Process Regulation Of Macroautophagy Ubiquitin-dependent ERAD Pathway Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Autophagosome Assembly	Phagocytosis Viral Process Macrophage Activation Neutrophil Degranulation Cell-cell Adhesion
Pathways		Cargo recognition for clathrin-mediated endocytosis	Neutrophil degranulation
Drugs
Diseases
GWAS			Liver enzyme levels (alanine transaminase) ( 24124411) Obesity-related traits ( 23251661) Venous thromboembolism ( 26888256 31676865)
Interacting Genes		22 interacting genes: ADRM1 ATXN7 BTRC C1QA CD93 FBXO25 FUS HERC3 HERPUD1 HNRNPA3 HSPA13 MTNR1B PRPF40A PSMA2 PSMA5 PSMD4 RNF11 RPN1 SMURF1 UBC UBE3A UBQLN4	23 interacting genes: ARHGAP15 BAG6 C1QA COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COPS5 F12 GIPC1 KIR2DL2 KNG1 MBL2 MSN MYD88 RANBP1 SCYL1 TENT5A UBQLN2
Entrez ID		29978	22918
HPRD ID		02224	00396
Ensembl ID		ENSG00000188021	ENSG00000125810
Uniprot IDs		Q9UHD9	Q9NPY3
PDB IDs		1J8C 2NBV 6MUN
Enriched GO Terms of Interacting Partners?
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