KLC2 and AIMP2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		KLC2	AIMP2
Description		kinesin light chain 2	aminoacyl tRNA synthetase complex interacting multifunctional protein 2
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex
	Molecular Function	Microtubule Motor Activity Protein Binding Kinesin Binding Cadherin Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)	Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		16 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 KIF2A KLC1 KLC4 LRRK2 MAPK8IP3 PIK3R3 PRC1 S100A8 YWHAG YWHAQ YWHAZ	48 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BYSL C19orf57 CEP126 CHD3 DARS1 DARS2 DEAF1 DSN1 EPRS1 EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS1 KDR KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 SMURF2 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT
Entrez ID		64837	7965
HPRD ID		13917	02915
Ensembl ID		ENSG00000174996	ENSG00000106305
Uniprot IDs		Q9H0B6	A0A024QZY1 A8MU58 Q13155
PDB IDs		3CEQ 3EDT	4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39
Enriched GO Terms of Interacting Partners?
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