AIMP2 and MIS18A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AIMP2	MIS18A
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 2	MIS18 kinetochore protein A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Molecular Adaptor Activity	Protein Binding Metal Ion Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity	Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Regulation Of DNA Methylation Cell Division
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation	Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS		Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		48 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BYSL C19orf57 CEP126 CHD3 DARS1 DARS2 DEAF1 DSN1 EPRS1 EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS1 KDR KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 SMURF2 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	7 interacting genes: AIMP2 BRD8 HJURP MAFIP MBIP NDEL1 ZNF471
Entrez ID		7965	54069
HPRD ID		02915	10749
Ensembl ID		ENSG00000106305	ENSG00000159055
Uniprot IDs		A0A024QZY1 A8MU58 Q13155	Q9NYP9
PDB IDs		4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39
Enriched GO Terms of Interacting Partners?
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