KLC2 and MAPK8IP3

Number of citations of the paper that reports this interaction (PubMedID 11106729)
116

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		KLC2	MAPK8IP3
Description		kinesin light chain 2	mitogen-activated protein kinase 8 interacting protein 3
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex	Golgi Membrane Cytoplasm Axon Dendrite Growth Cone Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm Axon Cytoplasm
	Molecular Function	Microtubule Motor Activity Protein Binding Kinesin Binding Cadherin Binding	MAP-kinase Scaffold Activity Protein Binding JUN Kinase Binding Kinesin Binding Receptor Signaling Complex Scaffold Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Activation Of JUN Kinase Activity Vesicle-mediated Transport Axon Regeneration Regulation Of JNK Cascade Axon Development Anterograde Axonal Protein Transport
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)	Intraocular pressure ( 29617998)
Interacting Genes		16 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 KIF2A KLC1 KLC4 LRRK2 MAPK8IP3 PIK3R3 PRC1 S100A8 YWHAG YWHAQ YWHAZ	23 interacting genes: ARL4D CASP3 KLC1 KLC2 LDLRAP1 MAP2K1 MAP2K4 MAP2K7 MAP3K11 MAP3K5 MAPK10 MAPK8 MAPK8IP1 MAPK8IP2 MAPK9 PTK2 RAD51 RAF1 RIC8A SRC TLR2 TLR4 TLR9
Entrez ID		64837	23162
HPRD ID		13917	12014
Ensembl ID		ENSG00000174996	ENSG00000138834
Uniprot IDs		Q9H0B6	A0A087WYG2 B7ZMF3 E9PFH7 Q9UPT6
PDB IDs		3CEQ 3EDT	4PXJ
Enriched GO Terms of Interacting Partners?
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