MAPK8IP3 and LDLRAP1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		MAPK8IP3	LDLRAP1
Description		mitogen-activated protein kinase 8 interacting protein 3	low density lipoprotein receptor adaptor protein 1
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Axon Dendrite Growth Cone Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm Axon Cytoplasm	Early Endosome Cytosol Neurofilament Plasma Membrane Cytoplasmic Side Of Plasma Membrane Basal Plasma Membrane Axon Clathrin-coated Vesicle Membrane Recycling Endosome
	Molecular Function	MAP-kinase Scaffold Activity Protein Binding JUN Kinase Binding Kinesin Binding Receptor Signaling Complex Scaffold Activity	Amyloid-beta Binding Phosphotyrosine Residue Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Receptor Signaling Complex Scaffold Activity Clathrin Binding Signaling Adaptor Activity AP-2 Adaptor Complex Binding Clathrin Adaptor Activity AP-1 Adaptor Complex Binding Low-density Lipoprotein Particle Receptor Binding
	Biological Process	Activation Of JUN Kinase Activity Vesicle-mediated Transport Axon Regeneration Regulation Of JNK Cascade Axon Development Anterograde Axonal Protein Transport	Receptor-mediated Endocytosis Cholesterol Metabolic Process Positive Regulation Of Signal Transduction Cholesterol Transport Receptor Internalization Low-density Lipoprotein Particle Clearance Cholesterol Homeostasis Amyloid Precursor Protein Metabolic Process Regulation Of Protein Binding Positive Regulation Of Receptor-mediated Endocytosis Membrane Organization Cellular Response To Cytokine Stimulus Receptor-mediated Endocytosis Involved In Cholesterol Transport Positive Regulation Of Cholesterol Metabolic Process Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Vascular Smooth Muscle Cell Proliferation Positive Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Chylomicron clearance LDL clearance
Drugs
Diseases
GWAS		Intraocular pressure ( 29617998)	Cholesterol, total ( 24097068 25961943 20686565) LDL cholesterol ( 24097068 25961943 20686565) LDL cholesterol levels ( 28334899) Mean platelet volume ( 27863252) Platelet count ( 27863252) Total cholesterol levels ( 28334899)
Interacting Genes		23 interacting genes: ARL4D CASP3 KLC1 KLC2 LDLRAP1 MAP2K1 MAP2K4 MAP2K7 MAP3K11 MAP3K5 MAPK10 MAPK8 MAPK8IP1 MAPK8IP2 MAPK9 PTK2 RAD51 RAF1 RIC8A SRC TLR2 TLR4 TLR9	9 interacting genes: AP2B1 APP C6orf58 CLTC LDLR LRP2 MAPK8IP3 PSD4 TFAP2A
Entrez ID		23162	26119
HPRD ID		12014	05765
Ensembl ID		ENSG00000138834	ENSG00000157978
Uniprot IDs		A0A087WYG2 B7ZMF3 E9PFH7 Q9UPT6	B3KR97 Q5SW96
PDB IDs		4PXJ	2G30
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?