EAF2 and TCEA2

Number of citations of the paper that reports this interaction (PubMedID 12761297)
3

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		EAF2	TCEA2
Description		ELL associated factor 2	transcription elongation factor A2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Nuclear Speck ELL-EAF Complex	Transcription Elongation Factor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Apoptotic Process Negative Regulation Of Cell Growth Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development	DNA-templated Transcription, Elongation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Adventurousness ( 30643258) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Pulse pressure ( 27841878 30578418) Serum thyroid-stimulating hormone levels ( 25436638) Systolic blood pressure ( 27841878) Triglyceride levels ( 29083408) Type 2 diabetes (adjusted for BMI) ( 30297969)
Interacting Genes		20 interacting genes: BEND7 BIRC2 ELL GOLGA2 HIF1A IHO1 LNX2 NECAB2 PNMA1 PSME3 RBPMS SSX2IP STAC3 TCEA1 TCEA2 TFIP11 TFPT TLE5 TP53 TRIM23	50 interacting genes: ADAMTSL4 AKT1S1 ALAS1 APP BRCA1 CAMKV CCDC136 CCSER2 CDK11B CENPT CEP44 DAB1 DCAF10 DHRS2 DNAJB9 EAF2 EXOSC8 FAM9B FBF1 GOLGA2 GPKOW GRIPAP1 GTF2B KIAA1958 KRT40 KRTAP10-7 KRTAP5-9 KXD1 LMNA LRRK2 LZTS2 MAGEA11 MARK3 MCM2 MEOX2 MID2 MKRN3 RPA1 SH3GL2 TAX1BP1 TAX1BP3 TCF4 TFCP2 THAP1 TNIP1 TRAF2 TRIM27 TRIM54 TSGA10 WDR47
Entrez ID		55840	6919
HPRD ID		09634	16069
Ensembl ID		ENSG00000145088	ENSG00000171703
Uniprot IDs		B4DWJ3 Q96CJ1	Q15560 Q6IB64
PDB IDs			2LW4
Enriched GO Terms of Interacting Partners?
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