TCEA2 and CENPT

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TCEA2	CENPT
Description		transcription elongation factor A2	centromere protein T
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Elongation Factor Complex	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	DNA-templated Transcription, Elongation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription By RNA Polymerase II	Mitotic Cell Cycle Regulation Of Transcription By RNA Polymerase II Chromosome Segregation CENP-A Containing Nucleosome Assembly Chromosome Organization Cell Division Kinetochore Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Pulse pressure ( 27841878 30578418) Serum thyroid-stimulating hormone levels ( 25436638) Systolic blood pressure ( 27841878) Triglyceride levels ( 29083408) Type 2 diabetes (adjusted for BMI) ( 30297969)	Schizophrenia ( 25056061 29483656)
Interacting Genes		50 interacting genes: ADAMTSL4 AKT1S1 ALAS1 APP BRCA1 CAMKV CCDC136 CCSER2 CDK11B CENPT CEP44 DAB1 DCAF10 DHRS2 DNAJB9 EAF2 EXOSC8 FAM9B FBF1 GOLGA2 GPKOW GRIPAP1 GTF2B KIAA1958 KRT40 KRTAP10-7 KRTAP5-9 KXD1 LMNA LRRK2 LZTS2 MAGEA11 MARK3 MCM2 MEOX2 MID2 MKRN3 RPA1 SH3GL2 TAX1BP1 TAX1BP3 TCF4 TFCP2 THAP1 TNIP1 TRAF2 TRIM27 TRIM54 TSGA10 WDR47	9 interacting genes: APP CENPW COPS5 CYB5B DHX29 H3C1 PPCDC SNCB TCEA2
Entrez ID		6919	80152
HPRD ID		16069	07811
Ensembl ID		ENSG00000171703	ENSG00000102901
Uniprot IDs		Q15560 Q6IB64	B3KPB2 Q96BT3
PDB IDs		2LW4
Enriched GO Terms of Interacting Partners?
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