EAF2 and BEND7

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid, two hybrid)

		EAF2	BEND7
Description		ELL associated factor 2	BEN domain containing 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Nuclear Speck ELL-EAF Complex	Extracellular Exosome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Protein Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Apoptotic Process Negative Regulation Of Cell Growth Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis (sporadic) ( 24529757) Diastolic blood pressure ( 30224653) Free thyroxine concentration ( 30367059) Skin pigmentation ( 28300201) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		20 interacting genes: BEND7 BIRC2 ELL GOLGA2 HIF1A IHO1 LNX2 NECAB2 PNMA1 PSME3 RBPMS SSX2IP STAC3 TCEA1 TCEA2 TFIP11 TFPT TLE5 TP53 TRIM23	34 interacting genes: BYSL CDCA7L CEP44 CHD2 CIB3 DDX6 DVL2 EAF1 EAF2 EIF1AD EMD FAM124A FAM133A L3MBTL2 LMO3 LYAR MFAP1 MORF4L1 MORF4L2 MYO15B NAP1L3 NIF3L1 NKAPD1 PIM1 PLEKHF2 PPIG PPP1R37 PSMF1 RAB29 SDCBP2 SMARCA2 U2AF2 USP20 ZCCHC10
Entrez ID		55840	222389
HPRD ID		09634	12570
Ensembl ID		ENSG00000145088	ENSG00000165626
Uniprot IDs		B4DWJ3 Q96CJ1	Q8N7W2
PDB IDs
Enriched GO Terms of Interacting Partners?
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