CDCA7L and PRDM14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CDCA7L	PRDM14
Description		cell division cycle associated 7 like	PR/SET domain 14
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytosol	Nucleus Nucleoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Germ Cell Development Embryo Implantation Fertilization Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Somatic Stem Cell Population Maintenance Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance
Pathways			Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Breast cancer ( 29059683) Height ( 20189936) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Pre-treatment viral load in HIV-1 infection ( 31219150) Squamous cell lung carcinoma ( 28604730) Urate levels in obese individuals ( 25811787)	Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		38 interacting genes: ABT1 ANKRD11 AXIN1 BEND7 BYSL CARD9 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 EIF4A3 FAM9B ING5 KRTAP10-7 LMO1 MDFI MFAP1 MLH1 MORN3 MYC NOP2 PPP1R16B PRDM14 PRPF31 SSX2IP STX11 SUV39H1 TADA2A TFPT TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZGPAT ZNF250 ZNF821	32 interacting genes: AKAP9 ATPAF2 BAG4 BCAR3 BEX2 CASP8 CDCA7L CHEK2 DGCR6 EED EIF4E2 ERBB2 EZH2 GPATCH2L HEXIM2 HSPB7 ID3 IDH1 MIA3 NDUFB9 PALB2 PAX2 PLEKHF2 PRKAB2 PSMA1 PTPRJ RAD51D RBM10 RCOR3 SUZ12 TEKT4 TTC32
Entrez ID		55536	63978
HPRD ID		11481	11457
Ensembl ID		ENSG00000164649	ENSG00000147596
Uniprot IDs		A0A024RA51 A8K8X5 Q96GN5	Q9GZV8
PDB IDs		5YI9 6EMO
Enriched GO Terms of Interacting Partners?
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