PRDM14 and NDUFB9

		PRDM14	NDUFB9
Description		PR/SET domain 14	NADH:ubiquinone oxidoreductase subunit B9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Germ Cell Development Embryo Implantation Fertilization Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Somatic Stem Cell Population Maintenance Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance	Mitochondrial Electron Transport, NADH To Ubiquinone Sensory Perception Of Sound Mitochondrial Respiratory Chain Complex I Assembly
Pathways		Transcriptional regulation of pluripotent stem cells	Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases
GWAS		Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		32 interacting genes: AKAP9 ATPAF2 BAG4 BCAR3 BEX2 CASP8 CDCA7L CHEK2 DGCR6 EED EIF4E2 ERBB2 EZH2 GPATCH2L HEXIM2 HSPB7 ID3 IDH1 MIA3 NDUFB9 PALB2 PAX2 PLEKHF2 PRKAB2 PSMA1 PTPRJ RAD51D RBM10 RCOR3 SUZ12 TEKT4 TTC32	19 interacting genes: DRC7 ELP1 EYA1 FEZ1 GDF9 HAP1 IMMT MAGEA11 MEF2A OR2D2 PRDM14 PRPF31 PSMB9 RAD54B RBBP6 SH3GL3 TNIP2 UBC XRN1
Entrez ID		63978	4715
HPRD ID		11457	03264
Ensembl ID		ENSG00000147596	ENSG00000147684
Uniprot IDs		Q9GZV8	E9PH64 Q9Y6M9
PDB IDs			5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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