PRDM14 and TEKT4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PRDM14	TEKT4
Description		PR/SET domain 14	tektin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Microtubule Cytoskeleton Sperm Flagellum
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Germ Cell Development Embryo Implantation Fertilization Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Somatic Stem Cell Population Maintenance Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance	Cilium Assembly Cilium Movement Involved In Cell Motility
Pathways		Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		32 interacting genes: AKAP9 ATPAF2 BAG4 BCAR3 BEX2 CASP8 CDCA7L CHEK2 DGCR6 EED EIF4E2 ERBB2 EZH2 GPATCH2L HEXIM2 HSPB7 ID3 IDH1 MIA3 NDUFB9 PALB2 PAX2 PLEKHF2 PRKAB2 PSMA1 PTPRJ RAD51D RBM10 RCOR3 SUZ12 TEKT4 TTC32	15 interacting genes: ALAS1 ATG5 GSE1 HNRNPM IKZF3 KRT15 KRTAP26-1 MAGEA4 PRDM14 RARA RECK SLC25A6 SMAD3 TADA2A TRIP6
Entrez ID		63978	150483
HPRD ID		11457	14518
Ensembl ID		ENSG00000147596	ENSG00000163060
Uniprot IDs		Q9GZV8	A0A384MEB7 Q8WW24
PDB IDs
Enriched GO Terms of Interacting Partners?
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