CHCHD3 and AMOTL2

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		CHCHD3	AMOTL2
Description		coiled-coil-helix-coiled-coil-helix domain containing 3	angiomotin like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane MICOS Complex Extracellular Exosome	Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome
	Molecular Function	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Phosphatase Binding Molecular Adaptor Activity	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation	Angiogenesis Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Wnt Signaling Pathway Actin Cytoskeleton Organization Regulation Of Cell Migration Hippo Signaling
Pathways		Mitochondrial protein import Cristae formation	Signaling by Hippo
Drugs
Diseases
GWAS		Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)	Cadmium levels ( 26025379) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
Interacting Genes		24 interacting genes: AASS AMOTL2 BLZF1 CALCOCO2 CBY2 CCDC33 CCDC85B FANCL GMCL2 GOLGA2 KRT40 KRTAP4-12 LZTS2 NOTCH2NLA NUDT3 PDE4DIP RAB3IP RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 USHBP1	57 interacting genes: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CHCHD3 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FBXO7 FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MTNR1A MYO5B NDC80 NFIL3 NTAQ1 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPOP SPP1 THRA TMCC2 TNKS2 TRAF2 TRIM27 ZBED1 ZGPAT
Entrez ID		54927	51421
HPRD ID		13044	16485
Ensembl ID		ENSG00000106554	ENSG00000114019
Uniprot IDs		A4D1N4 B7Z1X9 C9JRZ6 Q9NX63	Q9Y2J4
PDB IDs
Enriched GO Terms of Interacting Partners?
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