CHCHD3 and AASS

		CHCHD3	AASS
Description		coiled-coil-helix-coiled-coil-helix domain containing 3	aminoadipate-semialdehyde synthase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane MICOS Complex Extracellular Exosome	Cytoplasm Mitochondrion Mitochondrial Matrix Intracellular Membrane-bounded Organelle
	Molecular Function	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Phosphatase Binding Molecular Adaptor Activity	Saccharopine Dehydrogenase Activity Saccharopine Dehydrogenase (NADP+, L-lysine-forming) Activity Saccharopine Dehydrogenase (NAD+, L-glutamate-forming) Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation	Lysine Catabolic Process Lysine Biosynthetic Process Via Aminoadipic Acid L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Oxidation-reduction Process
Pathways		Mitochondrial protein import Cristae formation	Lysine catabolism
Drugs			Glutamic Acid NADH Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate N-(5-Amino-5-Carboxypentyl)Glutamic Acid
Diseases			Hyperlysinemia
GWAS		Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)
Interacting Genes		24 interacting genes: AASS AMOTL2 BLZF1 CALCOCO2 CBY2 CCDC33 CCDC85B FANCL GMCL2 GOLGA2 KRT40 KRTAP4-12 LZTS2 NOTCH2NLA NUDT3 PDE4DIP RAB3IP RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 USHBP1	6 interacting genes: ARF5 CCR6 CHCHD3 FSCN3 PTPRZ1 WASL
Entrez ID		54927	10157
HPRD ID		13044	05489
Ensembl ID		ENSG00000106554	ENSG00000008311
Uniprot IDs		A4D1N4 B7Z1X9 C9JRZ6 Q9NX63	A4D0W4 Q9UDR5
PDB IDs			5L76 5L78 5O1N 5O1O 5O1P
Enriched GO Terms of Interacting Partners?
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