S1PR5 and GNAO1

Number of citations of the paper that reports this interaction (PubMedID 11069896)
20

Data Source:
HPRD (in vitro)

		S1PR5	GNAO1
Description		sphingosine-1-phosphate receptor 5	G protein subunit alpha o1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Heterotrimeric G-protein Complex Plasma Membrane Dendrite Cell Body
	Molecular Function	Sphingosine-1-phosphate Receptor Activity	G Protein-coupled Receptor Binding GTPase Activity GTP Binding G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Serotonin Receptor Binding Mu-type Opioid Receptor Binding Metal Ion Binding Corticotropin-releasing Hormone Receptor 1 Binding
	Biological Process	Sphingosine-1-phosphate Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Regulation Of Neuron Differentiation	Protein Folding Muscle Contraction Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Dopamine Receptor Signaling Pathway Wnt Signaling Pathway, Calcium Modulating Pathway Locomotory Behavior Regulation Of Heart Contraction
Pathways		G alpha (i) signalling events Lysosphingolipid and LPA receptors	PLC beta mediated events PLC beta mediated events G-protein activation Ca2+ pathway Ca2+ pathway Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs		Fingolimod
Diseases
GWAS			Chronotype ( 30696823) Diastolic blood pressure ( 30578418) Dimensional psychopathology (Positive) ( 29496196) Metabolite levels ( 23823483) Mitochondrial DNA copy number ( 30704525) Morning person ( 30696823) Pulse pressure ( 27841878) Sleep duration (short sleep) ( 30846698)
Interacting Genes		3 interacting genes: GNA12 GNAI1 GNAO1	34 interacting genes: ADORA1 ADRA2A ADRA2C CACNA1B CCR5 CRHR1 DCTN2 FFAR2 GABBR1 GNAI1 GPSM2 GRM6 HRH4 KLHL3 NGB NUCB1 OPRD1 OPRM1 PDE6G PDE6H PTPRU RGS1 RGS10 RGS14 RGS16 RGS19 RGS20 RGS4 RGS5 RGS7 RIC8A S1PR5 SCN8A TSHR
Entrez ID		53637	2775
HPRD ID		05510	00757
Ensembl ID		ENSG00000180739	ENSG00000087258
Uniprot IDs		Q9H228	B3KP89 P09471 Q6AWC5 Q8N6I9
PDB IDs			6FUF 6G79 6OIK
Enriched GO Terms of Interacting Partners?
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