PDZK1 and SLC9A3R2

Number of citations of the paper that reports this interaction (PubMedID 14531806)
43

Data Source:
BioGRID (two hybrid)

		PDZK1	SLC9A3R2
Description		PDZ domain containing 1	SLC9A3 regulator 2
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GO Annotations	Cellular Component	Plasma Membrane Brush Border Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Exosome	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Scavenger Receptor Binding Protein Binding PDZ Domain Binding Protein-containing Complex Binding	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Carnitine Transport Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Anion Transport Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Protein Localization To Membrane Drug Transmembrane Export	Protein-containing Complex Assembly
Pathways
Drugs
Diseases
GWAS		Contrast sensitivity ( 24152035) Serum uric acid levels ( 30993211) Urate levels ( 20884846 31578528 23263486) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)	Diastolic blood pressure ( 27841878 30578418) Pulse pressure ( 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		29 interacting genes: ABCA1 ABCC2 ABCC4 AKAP10 APP CFTR CLCN3 CRHR1 FARP2 GFAP PDZK1IP1 PEX5 RPS6KA1 SCARB1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A1 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I	37 interacting genes: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A WWTR1
Entrez ID		5174	9351
HPRD ID		04829	05946
Ensembl ID		ENSG00000174827	ENSG00000065054
Uniprot IDs		Q5T2W1	Q15599
PDB IDs		2EEI 2EEJ 2VSP 3TMH 4Q2P 6EZI	2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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