PDZK1 and CLCN3

Number of citations of the paper that reports this interaction (PubMedID 12471024)
39

Data Source:
HPRD (in vivo, in vitro)

		PDZK1	CLCN3
Description		PDZ domain containing 1	chloride voltage-gated channel 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Brush Border Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Exosome	Golgi Membrane Cell Endosome Early Endosome Late Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle External Side Of Plasma Membrane Cell Surface Vesicle Membrane Membrane Integral Component Of Membrane Secretory Granule Transport Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Specific Granule Intracellular Membrane-bounded Organelle Phagocytic Vesicle
	Molecular Function	Scavenger Receptor Binding Protein Binding PDZ Domain Binding Protein-containing Complex Binding	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding ATP Binding Solute:proton Antiporter Activity PDZ Domain Binding Chloride Ion Binding Volume-sensitive Chloride Channel Activity
	Biological Process	Carnitine Transport Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Anion Transport Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Protein Localization To Membrane Drug Transmembrane Export	Regulation Of PH Negative Regulation Of Cell Volume Endosomal Lumen Acidification Chloride Transmembrane Transport Proton Transmembrane Transport
Pathways			Stimuli-sensing channels
Drugs
Diseases
GWAS		Contrast sensitivity ( 24152035) Serum uric acid levels ( 30993211) Urate levels ( 20884846 31578528 23263486) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)	Autism spectrum disorder or schizophrenia ( 28540026) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Schizophrenia ( 28991256 25056061 29483656 30285260)
Interacting Genes		29 interacting genes: ABCA1 ABCC2 ABCC4 AKAP10 APP CFTR CLCN3 CRHR1 FARP2 GFAP PDZK1IP1 PEX5 RPS6KA1 SCARB1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A1 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I	6 interacting genes: CFTR DNAJC5 GOPC HSPB1 PDZK1 SLC9A3R1
Entrez ID		5174	1182
HPRD ID		04829	02785
Ensembl ID		ENSG00000174827	ENSG00000109572
Uniprot IDs		Q5T2W1	B3KXK0 P51790
PDB IDs		2EEI 2EEJ 2VSP 3TMH 4Q2P 6EZI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?