LUC7L2 and EXOC1

Number of citations of the paper that reports this interaction (PubMedID 17043677)
168

Data Source:
BioGRID (two hybrid)

		LUC7L2	EXOC1
Description		LUC7 like 2, pre-mRNA splicing factor	exocyst complex component 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	U1 SnRNP Nuclear Speck U2-type Prespliceosome	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane
	Molecular Function	RNA Binding MRNA Binding Protein Binding Enzyme Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding GTP-Rho Binding
	Biological Process	MRNA Splice Site Selection	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Viral Process Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Exocyst Localization Defense Response To Virus
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132)	Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		51 interacting genes: AIMP2 ALB ANTKMT APP APPBP2 ATF7IP ATRX CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PABPC4 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRSF6 SVIL ULK2 UNC119 WASHC3 YWHAG ZCCHC10	27 interacting genes: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO
Entrez ID		51631	55763
HPRD ID		17456	07615
Ensembl ID		ENSG00000146963	ENSG00000090989
Uniprot IDs		Q9Y383	A0A024RDA1 A1LT29 Q9NV70
PDB IDs
Enriched GO Terms of Interacting Partners?
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