LUC7L2 and SVIL

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LUC7L2	SVIL
Description		LUC7 like 2, pre-mRNA splicing factor	supervillin
Image		No pdb structure
GO Annotations	Cellular Component	U1 SnRNP Nuclear Speck U2-type Prespliceosome	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere Invadopodium
	Molecular Function	RNA Binding MRNA Binding Protein Binding Enzyme Binding	Protein Binding Actin Filament Binding
	Biological Process	MRNA Splice Site Selection	Cytoskeleton Organization Skeletal Muscle Tissue Development Positive Regulation Of Cytokinesis
Pathways
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155)
Interacting Genes		51 interacting genes: AIMP2 ALB ANTKMT APP APPBP2 ATF7IP ATRX CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PABPC4 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRSF6 SVIL ULK2 UNC119 WASHC3 YWHAG ZCCHC10	36 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF14 KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG
Entrez ID		51631	6840
HPRD ID		17456	04992
Ensembl ID		ENSG00000146963	ENSG00000197321
Uniprot IDs		Q9Y383	O95425 Q569J5
PDB IDs			2K6M 2K6N
Enriched GO Terms of Interacting Partners?
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