APIP and CFAP206

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		APIP	CFAP206
Description		APAF1 interacting protein	cilia and flagella associated protein 206
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Radial Spoke Motile Cilium A Axonemal Microtubule
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Methylthioribulose 1-phosphate Dehydratase Activity	Protein Binding
	Biological Process	Apoptotic Process L-methionine Salvage From S-adenosylmethionine L-methionine Salvage From Methylthioadenosine Negative Regulation Of Apoptotic Process Protein Homotetramerization Pyroptosis Regulation Of ERK1 And ERK2 Cascade	Cilium Movement Axoneme Assembly
Pathways		Formation of apoptosome Methionine salvage pathway Regulation of the apoptosome activity
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797) Gamma glutamyl transferase levels ( 29403010) Lung disease severity in cystic fibrosis ( 26417704) Prostate-specific antigen levels ( 28139693) Systemic lupus erythematosus ( 19838195)
Interacting Genes		17 interacting genes: APAF1 CFAP206 IMPDH2 LNX1 NIF3L1 NTAQ1 NUDT18 PDZD4 PPP1CC PSMA1 SDCBP SKP1 TNPO2 TSC22D4 VIM VPS25 ZBTB25	27 interacting genes: ADAMTSL4 APIP ATPAF2 BANP C1orf94 CEP57L1 GFAP GLYR1 GPRASP2 GSE1 KLHL3 KRT31 KRT40 KRTAP13-1 LZTS2 MDFI RNF138 ROCK1 SAMD3 SOX30 TCF12 TFIP11 TLE5 TMCC2 UBXN11 USHBP1 ZBTB32
Entrez ID		51074	154313
HPRD ID		14725	12863
Ensembl ID		ENSG00000149089	ENSG00000272514
Uniprot IDs		Q96GX9	Q8IYR0 Q8N771
PDB IDs		4M6R
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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